More than 30 million adults are impacted by osteoarthritis, one of the most common forms of arthritis and disability. Osteoarthritis, a degenerative disease that causes gradual deterioration of cartilage within the joint, is the most common cause of joint pain. It happens with normal wear and tear over time. If you suffer from joint pain, you may be one of millions with osteoarthritis. Other types of degenerative joint disease that may cause pain include avascular necrosis (loss of bone due to insufficient blood flow), post-traumatic arthritis (brought on by injury), and rheumatoid arthritis (a chronic inflammatory condition).